Article
Efficient genotype elimination via adaptive allele consolidation.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
De Francesco Nicoletta, Lettieri Giuseppe, Martini Luca
Abstract excerpt
We propose the technique of Adaptive Allele Consolidation, that greatly improves the performance of the Lange-Goradia algorithm for genotype elimination in pedigrees, while still producing equivalent output. Genotype elimination consists in removing from a pedigree those genotypes that are impossible according to the Mendelian law of inheritance. This is used to find errors in genetic data and is useful as a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
