Article
TLR2 and TLR4 polymorphisms in Southern Chinese Psoriasis Vulgaris patients.
Journal of dermatological science - 1 Aug 2016
Shi Ge, Wang Tingting, Li Shijie, Cheng Yunlong, Sheng Ping, Fan Yiming, Zhu KunJu
Abstract excerpt
BACKGROUND: The toll-like receptors-(TLR)-2 and -4 play a role in the innate immune system and drive the autoimmune T cell cascade in psoriasis. But little is known about the association of the polymorphisms of TLR2/TLR4 and psoriasis vulgaris (PsV). METHODS: We performed a hospital-based association study involved in355 PsV patients and 213 controls. Genotyping of 11 SNPs rs4696480(-16934A/T), rs121917864...
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