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Article

Common ALDH2 genetic variants predict development of hypertension in the SAPPHIRe prospective cohort: gene-environmental interaction with alcohol consumption.

BMC cardiovascular disorders - 29 Jul 2012

Chang Yi-Cheng, Chiu Yen-Feng, Lee I-Te, Ho Low-Tone, Hung Yi-Jen, Hsiung Chao A, Quertermous Thomas, Donlon Timothy, Lee Wei-Jei, Lee Po-Chu, Chen Che-Hong, Mochly-Rosen Daria, Chuang Lee-Ming

Abstract excerpt

BACKGROUND: Genetic variants near/within the ALDH2 gene encoding the mitochondrial aldehyde dehydrogenase 2 have been associated with blood pressure and hypertension in several case-control association studies in East Asian populations. METHODS: Three common tag single nucleotide polymorphisms (tagSNP) in the ALDH2 gene were genotyped in 1,134 subjects of Chinese origin from the Stanford Asia-Pacific Program for...

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Identifiers

PMID: 22839215
DOI: 10.1186/1471-2261-12-58
PMCID: PMC3476438

Genes

ALDH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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