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Article

Gene-environmental interaction regarding alcohol-metabolizing enzymes in the Japanese general population.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 Mar 2009

Tsuchihashi-Makaya Miyuki, Serizawa Masakuni, Yanai Kazuyuki, Katsuya Tomohiro, Takeuchi Fumihiko, Fujioka Akihiro, Yamori Yukio, Ogihara Toshio, Kato Norihiro

Abstract excerpt

Epidemiological studies have shown that excessive alcohol consumption is a potent risk factor to develop hypertension. In addition, some polymorphisms of the alcohol metabolism genes have been reported to exert significant impacts on the risk of alcoholism. We investigate the relevance of genetic susceptibility to drinking behavior and its influence on the sensitivity to pressor effects of alcohol in the Japanese...

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Source

Identifiers

PMID: 19262484
DOI: 10.1038/hr.2009.3

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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