Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Candidate gene prioritization for chronic obstructive pulmonary disease using expression information in protein-protein interaction networks.

BMC pulmonary medicine - 4 Sept 2021

Li Wan, Zhang Yihua, Wang Yahui, Rong Zherou, Liu Chenyu, Miao Hui, Chen Hongwei, He Yuehan, He Weiming, Chen Lina

Abstract excerpt

BACKGROUND: Identifying or prioritizing genes for chronic obstructive pulmonary disease (COPD), one type of complex disease, is particularly important for its prevention and treatment. METHODS: In this paper, a novel method was proposed to Prioritize genes using Expression information in Protein-protein interaction networks with disease risks transferred between genes (abbreviated as PEP). A weighted COPD PPI...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Algorithms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Genetic Predisposition to Disease

Share to Protein Interaction Maps

Share to Pulmonary Disease, Chronic Obstructive

Share to Reproducibility of Results

Share to ROC Curve

Source

Open in PubMed Open full text

Identifiers

PMID: 34481483
DOI: 10.1186/s12890-021-01646-9
PMCID: PMC8418003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Candidate gene prioritization for chronic obstructive pulmonary disease using expression information in protein-protein interaction networks.PMID 34481483Read ↗

Chronic obstructive pulmonary disease candidate gene prioritization based on metabolic networks and functional information.Semantic proximity Read ↗

Prioritizing complex disease risk genes by integrating multiple data.Semantic proximity Read ↗

Microarray data-based prioritization of chronic obstructive pulmonary disease susceptibility genes.Semantic proximity Read ↗

Integrating gene expression and protein-protein interaction network to prioritize cancer-associated genesSemantic proximity Read ↗

Computational disease gene prioritization: an appraisal.Semantic proximity Read ↗

Identification of differentially expressed genes and signaling pathways in chronic obstructive pulmonary disease via bioinformatic analysisSemantic proximity Read ↗

Identifying key genes in COPD risk via multiple population data integration and gene prioritization.Semantic proximity Read ↗

Pathway centrality in protein interaction networks identifies functional mediators of pulmonary diseaseSemantic proximity Read ↗

Prioritising risk pathways of complex human diseases based on functional profiling.Semantic proximity Read ↗

GenePANDA-a novel network-based gene prioritizing tool for complex diseases.Semantic proximity Read ↗

A novel candidate disease genes prioritization method based on module partition and rank fusion.Semantic proximity Read ↗

GPEC: a Cytoscape plug-in for random walk-based gene prioritization and biomedical evidence collection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.