Article
Acquisition of clarithromycin resistance mutations in the 23S rRNA gene of Mycobacterium abscessus in the presence of inducible erm(41).
The Journal of antimicrobial chemotherapy - 1 Nov 2012
Maurer Florian P, Rüegger Vera, Ritter Claudia, Bloemberg Guido V, Böttger Erik C
Abstract excerpt
OBJECTIVES: Antibiotic therapy of pulmonary Mycobacterium abscessus infection is based on a combination treatment including clarithromycin. Recent data demonstrated that M. abscessus may carry a chromosomal, inducible erm gene coding for the ribosomal methylase Erm(41). The purpose of this study was to investigate whether in patients with chronic M. abscessus infection undergoing clarithromycin therapy, M....
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