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Article

Selection of Resistance to Clarithromycin in Mycobacterium abscessus Subspecies.

Antimicrobial agents and chemotherapy - 1 Jan 2017

Mougari Faiza, Bouziane Feriel, Crockett Flora, Nessar Rachid, Chau Françoise, Veziris Nicolas, Sapriel Guillaume, Raskine Laurent, Cambau Emmanuelle

Abstract excerpt

Mycobacterium abscessus is an emerging pathogen against which clarithromycin is the main drug used. Clinical failures are commonly observed and were first attributed to acquired mutations in rrl encoding 23S rRNA but were then attributed to the intrinsic production of the erm(41) 23S RNA methylase. Since strains of M. abscessus were recently distributed into subspecies and erm(41) sequevars, we investigated...

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Identifiers

PMID: 27799212
DOI: 10.1128/AAC.00943-16
PMCID: PMC5192163

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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