Article
Increased expression of receptor phosphotyrosine phosphatase-β/ζ is associated with molecular, cellular, behavioral and cognitive schizophrenia phenotypes.
Translational psychiatry - 10 May 2011
Takahashi N, Sakurai T, Bozdagi-Gunal O, Dorr N P, Moy J, Krug L, Gama-Sosa M, Elder G A, Koch R J, Walker R H, Hof P R, Davis K L, Buxbaum J D
Abstract excerpt
Schizophrenia is a serious and chronic mental disorder, in which both genetic and environmental factors have a role in the development of the disease. Neuregulin-1 (NRG1) is one of the most established genetic risk factors for schizophrenia, and disruption of NRG1 signaling has been reported in t...
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