Article
Increased bile resistance in Salmonella enterica mutants lacking Prc periplasmic protease.
International microbiology : the official journal of the Spanish Society for Microbiology - 1 Jun 2013
Hernández Sara B, Ayala Juan A, Rico-Pérez Gadea, García-del Portillo Francisco, Casadesús Josep
Abstract excerpt
Prc is a periplasmic protease involved in processing of penicillin-binding protein 3 (PBP3). Lack of Prc suppresses bile sensitivity in Dam-, Wec-, PhoP-, DamX-, and SeqA- mutants of Salmonella enterica, and increases bile resistance in the wild type. Changes in the activity of penicillin binding proteins PBP3, PBP4, PBP5/6 and PBP7 are detected in a Prc- background, suggesting that peptidoglycan remodeling might...
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