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Article

NlpI facilitates deposition of C4bp on Escherichia coli by blocking classical complement-mediated killing, which results in high-level bacteremia.

Infection and immunity - 1 Oct 2012

Tseng Yu-ting, Wang Shainn-Wei, Kim Kwang Sik, Wang Ying-Hsiang, Yao Yufeng, Chen Chien-Cheng, Chiang Chi-Wu, Hsieh Pao-Chuan, Teng Ching-Hao

Abstract excerpt

Neonatal meningitis Escherichia coli (NMEC) is the most common Gram-negative organism that is associated with neonatal meningitis, which usually develops as a result of hematogenous spread of the bacteria. There are two key pathogenesis processes for NMEC to penetrate into the brain, the essential step for the development of E. coli meningitis: a high-level bacteremia and traversal of the blood-brain barrier...

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Identifiers

PMID: 22802341
DOI: 10.1128/IAI.00320-12
PMCID: PMC3457581

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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