Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Negative regulators of integrin activity

1 Jan 2012

Abstract excerpt

Integrins are heterodimeric transmembrane adhesion receptors composed of α- and β-subunits. They are ubiquitously expressed and have key roles in a number of important biological processes, such as development, maintenance of tissue homeostasis and immunological responses. The activity of integrins, which indicates their affinity towards their ligands, is tightly regulated such that signals inside the cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules Research
Share to Cellular Mechanics and Interactions
Share to S100 Proteins and Annexins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22822081
DOI: 10.1242/jcs.093641

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Negative regulators of integrin activityPMID 22822081Read ↗

Integrin signalling and function in immune cellsSemantic proximity Read ↗

The dual structural roles of the membrane distal region of the α-integrin cytoplasmic tail during integrin inside-out activation.Semantic proximity Read ↗

Biology and structure of leukocyte β2 integrins and their role in inflammationSemantic proximity Read ↗

Integrins in regulation of tissue development and functionSemantic proximity Read ↗

Integrin Regulation during Leukocyte RecruitmentSemantic proximity Read ↗

β2 integrin activation and signal transduction in leukocyte recruitmentSemantic proximity Read ↗

Differential Binding of Active and Inactive Integrin to Talin.Semantic proximity Read ↗

SHARPIN is an endogenous inhibitor of β1-integrin activation.Semantic proximity Read ↗

Integrins in Health and Disease—Suitable Targets for Treatment?Semantic proximity Read ↗

Integrin StructureSemantic proximity Read ↗

Integrin StructureSemantic proximity Read ↗

Structural basis of kindlin-mediated integrin recognition and activation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.