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Article

Relation between flexibility and positively selected HIV-1 protease mutants against inhibitors.

Proteins - 1 Dec 2012

Braz Antônio S K, Tufanetto Patrícia, Perahia David, Scott Luis P B

Abstract excerpt

The antiretroviral chemotherapy helps to reduce the mortality of HIVs infected patients. However, RNA dependant virus replication has a high mutation rate. Human immunodeficiency virus Type 1 protease plays an essential role in viral replication cycle. This protein is an important target for ther...

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Identifiers

PMID: 22821809
DOI: 10.1002/prot.24151

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22821809-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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