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Article

Elasticity-Associated Functionality and Inhibition of the HIV Protease.

Advances in experimental medicine and biology - 1 Jan 2022

Sherry Dean, Worth Roland, Sayed Yasien

Abstract excerpt

HIV protease plays a critical role in the life cycle of the virus through the generation of mature and infectious virions. Detailed knowledge of the structure of the enzyme and its substrate has led to the development of protease inhibitors. However, the development of resistance to all currently available protease inhibitors has contributed greatly to the decreased success of antiretroviral therapy. When therapy...

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Identifiers

PMID: 34351572
DOI: 10.1007/5584_2021_655

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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