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Article

Structural studies on molecular mechanisms of Nelfinavir resistance caused by non-active site mutation V77I in HIV-1 protease.

BMC bioinformatics - 1 Jan 2015

Gupta Ankita, Jamal Salma, Goyal Sukriti, Jain Ritu, Wahi Divya, Grover Abhinav

Abstract excerpt

BACKGROUND: The human immunodeficiency virus (HIV-1) is a retrovirus causing acquired immunodeficiency syndrome (AIDS), which has become a serious problem across the world and has no cure reported to date. Human immunodeficiency virus (HIV-1) protease is an attractive target for antiviral treatment and a number of therapeutically useful inhibitors have been designed against it. The emergence of drug resistant...

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Identifiers

PMID: 26695135
DOI: 10.1186/1471-2105-16-S19-S10
PMCID: PMC4686784

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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