Article
Reversine promotes porcine muscle derived stem cells (PMDSCs) differentiation into female germ-like cells.
Journal of cellular biochemistry - 1 Dec 2012
Lv Xiao, Zhu Haijing, Bai Yaofu, Chu Zhili, Hu Yue, Cao Hui, Liu Chao, He Xin, Peng Sha, Gao Zhimin, Yang Chunrong, Hua Jinlian
Abstract excerpt
A small molecular chemical-Reversine has been shown to promote cell reprogramming and induce dedifferentiation of multiple terminally differentiated mesodermal origin cells, and then differentiate into other cell types within mesodermal lineages as well as neuroectodermal. However, the possibilities of these cells to give rise to germ cell lineages have not been examined. The objective of the current study was to...
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