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Effects of Growth Factors on In Vitro Culture of Neonatal Piglet Testicular Tissue Fragments

8 Sept 2023

Abstract excerpt

In vitro spermatogenesis (IVS) has important applications including fertility preservation of prepubertal cancer patients; however, thus far, IVS has only been achieved using mouse models. To study the effects of growth factors on the maintenance of testicular tissue integrity, germ cell numbers, and potential induction of IVS using a porcine model, we cultured small testicular fragments (~2 mg) from 1-wk-old...

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PMID: 37759457
DOI: 10.3390/cells12182234

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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