Article
Variability of GP6 gene in patients with sticky platelet syndrome and deep venous thrombosis and/or pulmonary embolism.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Sept 2012
Kotuličová Daniela, Chudý Peter, Škereňová Mária, Ivanková Jela, Dobrotová Miroslava, Kubisz Peter
Abstract excerpt
The GP6 gene encodes the GPVI, a crucial platelet membrane glycoprotein, for adequate platelet activation, adhesion and aggregation. The objectives of the present study were to assess the genetic variability of the GP6 gene in patients with platelet hyperaggregability phenotype, known as sticky platelet syndrome (SPS) manifesting as deep vein thrombosis (DVT), and/or pulmonary embolism, and in controls; and to...
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