Article
The prevalence of the platelet glycoprotein VI polymorphisms in patients with sticky platelet syndrome and ischemic stroke.
Hematology (Amsterdam, Netherlands) - 1 Nov 2012
Kubisz Peter, Ivanková Jela, Škereňová Mária, Staško Ján, Hollý Pavol
Abstract excerpt
INTRODUCTION: The aim of the study was to evaluate the genetic variability of the GP6 gene in patients with sticky platelet syndrome (SPS), a disorder characterized by platelet hyperaggregability, and thus to identify the genetic changes of the glycoprotein VI with possible relation to the platel...
Topics
- Adult
- Alleles
- Case-Control Studies
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Male
- Middle Aged
- Platelet Membrane Glycoproteins
- Polymorphism, Single Nucleotide
- Prevalence
- Stroke
- Syndrome
- Thrombophilia
- Young Adult