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PPARγ gene Pro12Ala variants reduce the risk of obese individuals to non-alcoholic fatty liver: A study in Uygur Chinese population residing in Northwestern China.

Clinics and research in hepatology and gastroenterology - 1 Nov 2020

Su Yinxia, Liu Zhenhui, Yang Lei, Li Yuanyuan, Jiang Sheng, Yao Hua, Du Guoli

Abstract excerpt

OBJECTIVE: To investigate the association of polymorphisms of Pro12Ala of peroxisome proliferator-activated receptor gamma (PPARγ) gene with clinical and biochemical parameters in Uygur Chinese population with non-alcoholic fatty liver (NAFLD) METHODS: In this case-control study, we recruited 467 NAFLD cases and 524 controls. Examination of abdominal ultrasound, clinical and biochemical profiles, as well as...

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PMID: 32505733
DOI: 10.1016/j.clinre.2020.02.005

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