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Article

The brain-derived neurotrophic factor (BDNF) gene Val66Met polymorphism affects memory performance in older adults.

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) - 1 Jan 2000

Azeredo Lucas A de, De Nardi Tatiana, Levandowski Mateus L, Tractenberg Saulo G, Kommers-Molina Julia, Wieck Andrea, Irigaray Tatiana Q, Silva Irênio G da, Grassi-Oliveira Rodrigo

Abstract excerpt

OBJECTIVE:: Memory impairment is an important contributor to the reduction in quality of life experienced by older adults, and genetic risk factors seem to contribute to variance in age-related cognitive decline. Brain-derived neurotrophic factor (BDNF) is an important nerve growth factor linked with development and neural plasticity. The Val66Met polymorphism in the BDNF gene has been associated with impaired...

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Identifiers

PMID: 28099630
DOI: 10.1590/1516-4446-2016-1980
PMCID: PMC7111449

Genes

BDNF

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Related research

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The brain-derived neurotrophic factor (BDNF) gene Val66Met polymorphism affects memory performance in older adults.PMID 28099630Read ↗

Impact of brain-derived neurotrophic factor genetic polymorphism on cognition: A systematic review.Semantic proximity Read ↗

Brain-derived neurotrophic factor polymorphism Val66Met influences cognitive abilities in the elderly.Semantic proximity Read ↗

Effect of BDNF val(66)met polymorphism on declarative memory and its neural substrate: a meta-analysis.Semantic proximity Read ↗

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Fine-mapping of the brain-derived neurotrophic factor (BDNF) gene supports an association of the Val66Met polymorphism with episodic memory.Semantic proximity Read ↗

The brain-derived neurotrophic factor Val66Met polymorphism, hippocampal volume, and cognitive function in geriatric depression.Semantic proximity Read ↗

Association between BDNF val66 met genotype and episodic memory.Semantic proximity Read ↗

Brain-derived neurotrophic factor (BDNF) gene: a gender-specific role in cognitive function during normal cognitive aging of the MEMO-Study?Semantic proximity Read ↗

The implication of BDNF Val66Met polymorphism in progression from subjective cognitive decline to mild cognitive impairment and Alzheimer’s disease: a 9-year follow-up studySemantic proximity Read ↗

BDNF Val66Met polymorphism is associated with consolidation of episodic memory during sleep.Semantic proximity Read ↗

Overestimation of the effects of the BDNF val66met polymorphism on episodic memory-related hippocampal function: a critique of a recent meta-analysis.Semantic proximity Read ↗

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