Mendelian Randomisation Analysis of Causal Association between Lifestyle, Health Factors, and Keratoconus

Abstract excerpt

Keratoconus (KC), a leading cause of vision impairment, has an unclear aetiology. This study used Mendelian randomization (MR) to explore the causal links between various factors (smoking, asthma, Down syndrome, inflammatory bowel disease, atopic dermatitis, and serum 25-hydroxyvitamin D levels) and KC. A two-sample MR design, grounded in genome-wide association study (GWAS) summary statistics, was adopted using...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Corneal surgery and disorders
• Share to Glaucoma and retinal disorders
• Share to Ocular Surface and Contact Lens