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Article

Dnt1 acts as a mitotic inhibitor of the spindle checkpoint protein dma1 in fission yeast.

Molecular biology of the cell - 1 Sept 2012

Wang Yamei, Li Wen-zhu, Johnson Alyssa E, Luo Zhou-qing, Sun Xue-li, Feoktistova Anna, McDonald W Hayes, McLeod Ian, Yates John R, Gould Kathleen L, McCollum Dannel, Jin Quan-wen

Abstract excerpt

The Schizosaccharomyces pombe checkpoint protein Dma1 couples mitotic progression with cytokinesis and is important in delaying mitotic exit and cytokinesis when kinetochores are not properly attached to the mitotic spindle. Dma1 is a ubiquitin ligase and potential functional relative of the human tumor suppressor Chfr. Dma1 delays mitotic exit and cytokinesis by ubiquitinating a scaffold protein (Sid4) of the...

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Identifiers

PMID: 22809626
DOI: 10.1091/mbc.E11-12-1020
PMCID: PMC3431938

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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