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Study of rifampicin and isoniazid resistance mutation genes of M. tuberculosis isolates in Nepal.

Nepal Medical College journal : NMCJ - 1 Sept 2011

Khadka J B, Rai S K, Shrestha S, Maharjan B, Bhatta D R, Ghimire P

Abstract excerpt

We studied the rifampicin (RIF) and isoniazid (INH) resistant genes in Mycobacterium tuberculosis isolated from sputum samples of re-treated TB cases using phenotypic drug susceptibility test (DST) and rapid molecular method (Genotype; MTBDR plus, Hains Life Science, Nehren, Germany). Of the total 207 isolates included in this study, 90 (42.0%) were RIF resistant, 107 (50.7%) were INH resistant whereas 86 (41.5%)...

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PMID: 22808802

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DST

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