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Article

Sleep phenotyping in a mouse model of extreme trait anxiety.

PloS one - 1 Jan 2012

Jakubcakova Vladimira, Flachskamm Cornelia, Landgraf Rainer, Kimura Mayumi

Abstract excerpt

BACKGROUND: There is accumulating evidence that anxiety impairs sleep. However, due to high sleep variability in anxiety disorders, it has been difficult to state particular changes in sleep parameters caused by anxiety. Sleep profiling in an animal model with extremely high vs. low levels of trait anxiety might serve to further define sleep patterns associated with this psychopathology. METHODOLOGY/PRINCIPAL...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22808211
DOI: 10.1371/journal.pone.0040625
PMCID: PMC3394752

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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