Article
Cellular variability of RpoS expression underlies subpopulation activation of an integrative and conjugative element.
PLoS genetics - 1 Jan 2012
Miyazaki Ryo, Minoia Marco, Pradervand Nicolas, Sulser Sandra, Reinhard Friedrich, van der Meer Jan Roelof
Abstract excerpt
Conjugative transfer of the integrative and conjugative element ICEclc in the bacterium Pseudomonas knackmussii is the consequence of a bistable decision taken in some 3% of cells in a population during stationary phase. Here we study the possible control exerted by the stationary phase sigma factor RpoS on the bistability decision. The gene for RpoS in P. knackmussii B13 was characterized, and a loss-of-function...
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