Article

Clinical stringent response activation promotes conjugal transfer of staphylococcal resistance plasmids

2025-11-12

Abstract excerpt

<h4>ABSTRACT</h4> Conjugative transfer of plasmids represents a major route through which antibiotic resistance genes are spread. In the case of the prevalent and deadly pathogen Staphylococcus aureus , >90% of clinical isolates carry at least one plasmid. While plasmid-encoded mechanisms ( e.g. plasmid copy number) can influence conjugation frequency, host factors and environmental stimuli can also affect tran...

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Literature Corpus work: f5158fe5-13f0-5f8b-9d3f-38269e016378
DOI: 10.1101/2025.11.12.688057

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