Article
Post-transcriptionally generated cell heterogeneity regulates biofilm formation in Bacillus subtilis.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Apr 2016
Ogura Mitsuo
Abstract excerpt
Bacillus subtilis forms biofilms in appropriate environments by producing extracellular matrices. Genes required for matrix formation, for example tapA, are regulated by the SinI/SinR/SlrR system. SinR is the repressor for tapA. SinI and SlrR inhibit DNA-binding of SinR. sinI and sinR constitute two-gene operon, and sinR has its own promoter. During biofilm formation, a portion of the population differentiates...
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