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Article

APC mutation and tumour budding in colorectal cancer.

Journal of clinical pathology - 1 Jan 2003

Jass J R, Barker M, Fraser L, Walsh M D, Whitehall V L J, Gabrielli B, Young J, Leggett B A

Abstract excerpt

AIM: To determine the frequency of tumour budding and somatic APC mutation in a series of colorectal cancers stratified according to DNA microsatellite instability (MSI) status. MATERIAL/METHODS: Ninety five colorectal cancers were genotyped for APC mutation in the mutation cluster region (exon 15) and scored for the presence of tumour budding at the invasive margin in haematoxylin and eosin stained sections. A...

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Identifiers

PMID: 12499439
DOI: 10.1136/jcp.56.1.69
PMCID: PMC1769852

Genes

APC

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Source receipt: pubmed, retrieved 7 Sept 2026.

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