Article
Association analysis of cytokine polymorphisms and plasma level in Northern Chinese Han patients with paroxysmal nocturnal hemoglobinuria.
Chinese medical journal - 1 May 2012
Wang Shu-Ye, Yang Xi-Jing, Yang Shan-Shan, Wang Wei, Tian Yao-Yao, Cao Feng-Lin, Zhou Jin
Abstract excerpt
BACKGROUND: While the incidence of paroxysmal nocturnal hemoglobinuria (PNH) is relatively high in Northern China, the exact mechanism of the disease remains unknown. Immunoregulatory cytokine polymorphisms can directly regulate the expression levels of cytokines, which play a crucial role in many diseases. The purpose of this study was to study cytokine gene single nucleotide polymorphisms (SNPs) and the...
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