Article
Restored function of HBV-specific T cells after long-term effective therapy with nucleos(t)ide analogues.
Gastroenterology - 1 Oct 2012
Boni Carolina, Laccabue Diletta, Lampertico Pietro, Giuberti Tiziana, Viganò Mauro, Schivazappa Simona, Alfieri Arianna, Pesci Marco, Gaeta Giovanni B, Brancaccio Giuseppina, Colombo Massimo, Missale Gabriele, Ferrari Carlo
Abstract excerpt
BACKGROUND & AIMS: In patients with chronic hepatitis B virus (HBV) infection, persistent exposure to high concentrations of antigen can disrupt T-cell functions. It is not clear to what extent long-term suppression of HBV by nucleos(t)ide analogues can restore antiviral T-cell functions. We comp...
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