Article
A histone-like protein of Helicobacter pylori protects DNA from stress damage and aids host colonization.
DNA repair - 1 Sept 2012
Wang Ge, Lo Leja F, Maier Robert J
Abstract excerpt
Genomic DNA in a bacterial cell is folded into a compact structure called a nucleoid, and nucleoid-associated proteins are responsible for proper assembly of active higher-order genome structures. The human gastric pathogen Helicobacter pylori express a nucleoid-associated protein encoded by the hup gene, which is the homolog to the Escherichia coli histone-like protein HU. An H. pylori hup mutant strain (X47...
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