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Article

Genetic Diversity as Consequence of a Microaerobic and Neutrophilic Lifestyle.

PLoS pathogens - 1 May 2016

Krüger Nora-Johanna, Knüver Marie-Theres, Zawilak-Pawlik Anna, Appel Bernd, Stingl Kerstin

Abstract excerpt

As a neutrophilic bacterium, Helicobacter pylori is growth deficient under extreme acidic conditions. The gastric pathogen is equipped with an acid survival kit, regulating urease activity by a pH-gated urea channel, opening below pH 6.5. After overcoming acid stress, the bacterium's multiplication site is situated at the gastric mucosa with near neutral pH. The pathogen exhibits exceptional genetic variability,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27166672
DOI: 10.1371/journal.ppat.1005626
PMCID: PMC4864210

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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