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Article

Novel nuclear targeting coiled-coil protein of Helicobacter pylori showing Ca(2+)-independent, Mg(2+)-dependent DNase I activity.

Journal of microbiology (Seoul, Korea) - 1 May 2016

Kwon Young Chul, Kim Sinil, Lee Yong Seok, Lee Je Chul, Cho Myung-Je, Lee Woo-Kon, Kang Hyung-Lyun, Song Jae-Young, Baik Seung Chul, Ro Hyeon Su

Abstract excerpt

HP0059, an uncharacterized gene of Helicobacter pylori, encodes a 284-aa-long protein containing a nuclear localization sequence (NLS) and multiple leucine-rich heptad repeats. Effects of HP0059 proteins in human stomach cells were assessed by incubation of recombinant HP0059 proteins with the AGS human gastric carcinoma cell line. Wild-type HP0059 proteins showed cytotoxicity in AGS cells in a...

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PMID: 27095458
DOI: 10.1007/s12275-016-5631-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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