Article
Spliceosomal gene mutations are frequent events in the diverse mutational spectrum of chronic myelomonocytic leukemia but largely absent in juvenile myelomonocytic leukemia.
Haematologica - 1 Jan 2013
Kar Sarah Abu, Jankowska Anna, Makishima Hideki, Visconte Valeria, Jerez Andres, Sugimoto Yuka, Muramatsu Hideki, Traina Fabiola, Afable Manuel, Guinta Kathryn, Tiu Ramon V, Przychodzen Bartlomiej, Sakaguchi Hirotoshi, Kojima Seiji, Sekeres Mikkael A, List Alan F, McDevitt Michael A, Maciejewski Jaroslaw P
Abstract excerpt
Chronic myelomonocytic leukemia is a heterogeneous disease with multifactorial molecular pathogenesis. Various recurrent somatic mutations have been detected alone or in combination in chronic myelomonocytic leukemia. Recently, recurrent mutations in spliceosomal genes have been discovered. We in...
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