Article
Impact of the -174G/C interleukin-6 (IL-6) gene polymorphism on the risk of paediatric ischemic stroke, its symptoms and outcome.
Folia neuropathologica - 1 Jan 2012
Balcerzyk Anna, Nowak Marta, Kopyta Ilona, Emich-Widera Ewa, Pilarska Ewa, Pienczk-Ręcławowicz Karolina, Kaciński Marek, Wendorff Janusz, Zak Iwona
Abstract excerpt
OBJECTIVES: Ischemic stroke remains one of the top ten causes of death in children. There is evidence for the role of pro-inflammatory cytokines, such as IL-6 and the -174G>C promoter polymorphism of the IL-6 gene, in the occurrence and outcome of stroke in adults. The aim of the present study was to determine a possible association between the -174G>C IL-6 polymorphism and occurrence of paediatric stroke, its...
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