Article
Genetic variants associated with susceptibility to mother-to-child transmission of hepatitis B virus.
European journal of gastroenterology & hepatology - 1 Oct 2012
Chatzidaki Virginia, Choumerianou Despoina, Dimitriou Helen, Kouroumalis Elias, Galanakis Emmanouil
Abstract excerpt
OBJECTIVE: The mechanisms of immune tolerance to hepatitis B virus (HBV) in children infected perinatally or early in infancy still remain unclarified. We aimed to study the genetic variants of immune factors implicated in viral-host interaction in children who were born to HBV-positive mothers and who had different clinical outcome. METHODS: Mannose-binding lectin gene (mbl2) codon 54, codon 57, and promoter 221...
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