Article
Virologic characteristics of hepatitis B virus in patients infected via maternal-fetal transmission.
World journal of gastroenterology - 7 Oct 2008
Shen Tao, Yan Xin-Min, Zou Yun-Lian, Gao Jian-Mei, Dong Hong
Abstract excerpt
AIM: To determine whether HBV with the same characteristics causes dissimilar mutations in different hosts. METHODS: Full-length HBV genome was amplified and linked with pMD T18 vector. Positive clones were selected by double-restriction endonuclease digestion (EcoRI and HindIII) and PCR. Twenty seven clones were randomly selected from an asymptomatic mother [at two time points: 602 (1 d) and 6022 (6 mo)] and her...
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