Article
Association of HLA and TNF polymorphisms with the outcome of HBV infection in the South Indian population.
Genes and immunity - 1 Oct 2011
Fletcher G J, Samuel P, Christdas J, Gnanamony M, Ismail A M, Anantharam R, Eapen C E, Chacko M P, Daniel D, Kannangai R, Abraham P
Abstract excerpt
The role of host genetic factors in the pathogenesis and outcome of hepatitis B virus (HBV) infection is not well known. We assessed the association of HLA and TNF (rs361525, rs1800629, rs1799724, rs1800630 and rs1799964) polymorphisms with HBV outcome in the South Indian population. Association of HLA polymorphism was analyzed in 90 individuals from each group, that is, spontaneous recovery (SR) and chronic-HBV...
