Article
WNT7A.
Differentiation; research in biological diversity - 1 Jan 2025
Calhoun Naomi M, Behringer Richard R
Abstract excerpt
WNT7A regulates numerous developmental processes. It can activate canonical and non-canonical signaling depending on context. It is expressed in the developing central nervous system, limb buds, reproductive organs, and other tissues. Spontaneous and targeted Wnt7a mutations in mouse models resulted in abnormal limbs, defects in male and female reproductive tract organs, infertility, and defects in cerebellar...
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