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Article

Epstein-Barr virus BGLF4 kinase retards cellular S-phase progression and induces chromosomal abnormality.

PloS one - 1 Jan 2012

Chang Yu-Hsin, Lee Chung-Pei, Su Mei-Tzu, Wang Jiin-Tarng, Chen Jen-Yang, Lin Su-Fang, Tsai Ching-Hwa, Hsieh Min-Jei, Takada Kenzo, Chen Mei-Ru

Abstract excerpt

Epstein-Barr virus (EBV) induces an uncoordinated S-phase-like cellular environment coupled with multiple prophase-like events in cells replicating the virus. The EBV encoded Ser/Thr kinase BGLF4 has been shown to induce premature chromosome condensation through activation of condensin and topois...

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Identifiers

PMID: 22768064
DOI: 10.1371/journal.pone.0039217
PMCID: PMC3387188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22768064-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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