Article
Modification of neurobehavioral effects of mercury by a genetic polymorphism of coproporphyrinogen oxidase in children.
Neurotoxicology and teratology - 1 Jan 2000
Woods James S, Heyer Nicholas J, Echeverria Diana, Russo Joan E, Martin Michael D, Bernardo Mario F, Luis Henrique S, Vaz Lurdes, Farin Federico M
Abstract excerpt
Mercury (Hg) is neurotoxic, and children may be particularly susceptible to this effect. A current major challenge is the identification of children who may be uniquely susceptible to Hg toxicity because of genetic disposition. We examined the hypothesis that CPOX4, a genetic variant of the heme pathway enzyme coproporphyrinogen oxidase (CPOX) that affects susceptibility to mercury toxicity in adults, also...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.