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FusionFinder: A Software Tool to Identify Expressed Gene Fusion Candidates from RNA-Seq Data

27 Jun 2012

Abstract excerpt

The hallmarks of many haematological malignancies and solid tumours are chromosomal translocations, which may lead to gene fusions. Recently, next-generation sequencing techniques at the transcriptome level (RNA-Seq) have been used to verify known and discover novel transcribed gene fusions. We present FusionFinder, a Perl-based software designed to automate the discovery of candidate gene fusion partners from...

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PMID: 22761941
DOI: 10.1371/journal.pone.0039987

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