Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel Fusion of MYST/Esa1-Associated Factor 6 and PHF1 in Endometrial Stromal Sarcoma

22 Jun 2012

Abstract excerpt

Rearrangement of chromosome band 6p21 is recurrent in endometrial stromal sarcoma (ESS) and targets the PHF1 gene. So far, PHF1 was found to be the 3' partner in the JAZF1-PHF1 and EPC1-PHF1 chimeras but since the 6p21 rearrangements involve also other chromosomal translocation partners, other PHF1-fusions seem likely. Here, we show that PHF1 is recombined with a novel fusion partner, MEAF6 from 1p34, in an ESS...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Sarcoma Diagnosis and Treatment
Share to Uterine Myomas and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22761769
DOI: 10.1371/journal.pone.0039354

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel Fusion of MYST/Esa1-Associated Factor 6 and PHF1 in Endometrial Stromal SarcomaPMID 22761769Read ↗

Recurrent chromosomal translocations in sarcomas create a mega-complex that mislocalizes NuA4/TIP60 to Polycomb target lociSemantic proximity Read ↗

Consistent Rearrangement of Chromosomal Band 6p21 with Generation of Fusion Genes<i>JAZF1/PHF1</i>and<i>EPC1/PHF1</i>in Endometrial Stromal SarcomaSemantic proximity Read ↗

Identification of anEPC2-PHF1fusion transcript in low-grade endometrial stromal sarcomaSemantic proximity Read ↗

Recurrent rearrangement of the PHF1 gene in ossifying fibromyxoid tumors.Semantic proximity Read ↗

Molecular and clinical analyses of PHF6 mutant myeloid neoplasia provide their pathogenesis and therapeutic targeting.Semantic proximity Read ↗

JAZF1/SUZ12 gene fusion in endometrial stromal sarcomasSemantic proximity Read ↗

Fusion of the <i>ZC3H7B</i> and <i>BCOR</i> genes in endometrial stromal sarcomas carrying an X;22‐translocationSemantic proximity Read ↗

Frequency of Known Gene Rearrangements in Endometrial Stromal TumorsSemantic proximity Read ↗

The t(6;8)(q27;p11) Translocation in a Stem Cell Myeloproliferative Disorder Fuses a Novel Gene, FOP, to Fibroblast Growth Factor Receptor 1Semantic proximity Read ↗

Fusion of the Genes PHF1 and TFE3 in Malignant Chondroid SyringomaSemantic proximity Read ↗

MEAF6 is essential for cell proliferation and plays a role in the assembly of KAT7 complexes.Semantic proximity Read ↗

Cloning of an <i>Alpha-TFEB</i> fusion in renal tumors harboring the t(6;11)(p21;q13) chromosome translocationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.