Article
Recurrent rearrangement of the PHF1 gene in ossifying fibromyxoid tumors.
The American journal of pathology - 1 Sept 2012
Gebre-Medhin Samuel, Nord Karolin H, Möller Emely, Mandahl Nils, Magnusson Linda, Nilsson Jenny, Jo Vickie Y, Vult von Steyern Fredrik, Brosjö Otte, Larsson Olle, Domanski Henryk A, Sciot Raf, Debiec-Rychter Maria, Fletcher Christopher D M, Mertens Fredrik
Abstract excerpt
Ossifying fibromyxoid tumor (OFMT) is a soft tissue tumor of unknown lineage. Although most cases are histologically and clinically benign, some show malignant morphological features and local recurrences are not uncommon; a few may even metastasize. In the present study, cytogenetic analysis identified different structural rearrangements of chromosome band 6p21 in tumor cells from three cases of OFMT, including...
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