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Consistent Rearrangement of Chromosomal Band 6p21 with Generation of Fusion Genes<i>JAZF1/PHF1</i>and<i>EPC1/PHF1</i>in Endometrial Stromal Sarcoma

1 Jan 2006

Abstract excerpt

Endometrial stromal sarcomas (ESS) represent <10% of all uterine sarcomas. Cytogenetic data on this tumor type are limited to 32 cases, and the karyotypes are often complex, but the pattern of rearrangement is nevertheless clearly nonrandom with particularly frequent involvement of chromosome arms 6p and 7p. Recently, a specific translocation t(7;17)(p15;q21) leading to the fusion of two zinc finger genes,...

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PMID: 16397222
DOI: 10.1158/0008-5472.can-05-2485

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