Article
Viral perturbations of host networks reflect disease etiology.
PLoS computational biology - 1 Jan 2012
Gulbahce Natali, Yan Han, Dricot Amélie, Padi Megha, Byrdsong Danielle, Franchi Rachel, Lee Deok-Sun, Rozenblatt-Rosen Orit, Mar Jessica C, Calderwood Michael A, Baldwin Amy, Zhao Bo, Santhanam Balaji, Braun Pascal, Simonis Nicolas, Huh Kyung-Won, Hellner Karin, Grace Miranda, Chen Alyce, Rubio Renee, Marto Jarrod A, Christakis Nicholas A, Kieff Elliott, Roth Frederick P, Roecklein-Canfield Jennifer, Decaprio James A, Cusick Michael E, Quackenbush John, Hill David E, Münger Karl, Vidal Marc, Barabási Albert-László
Abstract excerpt
Many human diseases, arising from mutations of disease susceptibility genes (genetic diseases), are also associated with viral infections (virally implicated diseases), either in a directly causal manner or by indirect associations. Here we examine whether viral perturbations of host interactome...
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