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Article

A candidate gene approach for virally induced cancer with application to HIV-related Kaposi's sarcoma.

International journal of cancer - 15 Jan 2014

Aissani Brahim, Wiener Howard W, Zhang Kui, Kaslow Richard A, Ogwaro Kisani M, Shrestha Sadeep, Jacobson Lisa P

Abstract excerpt

Like other members of the γ-herpesvirus family, human herpes virus 8, the etiologic agent of classic and HIV-related Kaposi's sarcoma (HIV-KS) acquired and evolved several human genes with key immune modulatory and cellular growth control functions. The encoded viral homologs substitute for their human counterparts but escape cellular regulation, leading to uncontrolled cell proliferation. We postulated that DNA...

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Source

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Identifiers

PMID: 23818101
DOI: 10.1002/ijc.28351
PMCID: PMC4007164

Genes

CCL2
CCND1
CFLAR
EDNRB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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