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Article

Network modeling suggests HIV infection phenocopies PI3K-AKT pathway mutations to enhance HPV-associated cervical cancer.

Molecular omics - 14 Aug 2023

Olwal Charles Ochieng', Fabius Jacqueline M, Zuliani-Alvarez Lorena, Eckhardt Manon, Kyei George Boateng, Quashie Peter Kojo, Krogan Nevan J, Bouhaddou Mehdi, Bediako Yaw

Abstract excerpt

Women coinfected with human immunodeficiency virus type 1 (HIV-1) and human papillomavirus (HPV) are six times as likely to develop invasive cervical carcinoma compared to those without HIV. Unlike other HIV-associated cancers, the risk of cervical cancer development does not change when HPV/HIV coinfected women begin antiretroviral therapy, suggesting HIV-associated immune suppression is not a key driver of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37204043
DOI: 10.1039/d3mo00025g
PMCID: PMC10524288

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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