Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nasopharyngeal colonization and invasive disease are enhanced by the cell wall hydrolases LytB and LytC of Streptococcus pneumoniae.

PloS one - 1 Jan 2011

Ramos-Sevillano Elisa, Moscoso Miriam, García Pedro, García Ernesto, Yuste Jose

Abstract excerpt

BACKGROUND: Streptococcus pneumoniae is a common colonizer of the human nasopharynx and one of the major pathogens causing invasive disease worldwide. Dissection of the molecular pathways responsible for colonization, invasion, and evasion of the immune system will provide new targets for antimicrobial or vaccine therapies for this common pathogen. METHODOLOGY/PRINCIPAL FINDINGS: We have constructed mutants...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colony Count, Microbial
Share to Complement C3b

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydrolases

Share to Macrophages, Alveolar

Share to N-Acetylmuramoyl-L-alanine Amidase

Share to Nasopharynx

Share to Pneumococcal Infections

Share to Sepsis

Source

Open in PubMed Open full text

Identifiers

PMID: 21886805
DOI: 10.1371/journal.pone.0023626
PMCID: PMC3160309

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nasopharyngeal colonization and invasive disease are enhanced by the cell wall hydrolases LytB and LytC of Streptococcus pneumoniae.PMID 21886805Read ↗

Macrolides and β-lactam antibiotics enhance C3b deposition on the surface of multidrug-resistant Streptococcus pneumoniae strains by a LytA autolysin-dependent mechanism.Semantic proximity Read ↗

Pathogenesis of pneumococcal infectionSemantic proximity Read ↗

The choline-binding proteins PspA, PspC and LytA of <i>Streptococcus pneumoniae</i> and their role on host cellular adhesion and damageSemantic proximity Read ↗

Structure, Function, and Regulation of LytA: The N-Acetylmuramoyl-l-alanine Amidase Driving the “Suicidal Tendencies” of Streptococcus pneumoniae—A ReviewSemantic proximity Read ↗

Structure, Function, and Regulation of LytA: The N-Acetylmuramoyl-L-alanine Amidase Driving the ‘Suicidal Tendencies’ of Streptococcus pneumoniae— A ReviewSemantic proximity Read ↗

Molecular pathogenesis of pneumococcal pneumoniaSemantic proximity Read ↗

Dynamic capsule restructuring by the main pneumococcal autolysin LytA in response to the epithelium.Semantic proximity Read ↗

Structure of the pneumococcal l,d-carboxypeptidase DacB and pathophysiological effects of disabled cell wall hydrolases DacA and DacB.Semantic proximity Read ↗

Rapid killing of Streptococcus pneumoniae with a bacteriophage cell wall hydrolase.Semantic proximity Read ↗

Emerging concepts in the pathogenesis of theStreptococcus pneumoniae: From nasopharyngeal colonizer to intracellular pathogenSemantic proximity Read ↗

The virulence factors and pathogenic mechanisms of Streptococcus pyogenesSemantic proximity Read ↗

Capsular polysaccharide enables Klebsiella pneumoniae to evade phagocytosis by blocking host-bacteria interactionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.