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Regulation of neuraminidase expression in Streptococcus pneumoniae

11 Sept 2012

Abstract excerpt

BACKGROUND: Sialic acid (N-acetylneuraminic acid; NeuNAc) is one of the most important carbohydrates for Streptococcus pneumoniae due of its role as a carbon and energy source, receptor for adhesion and invasion and molecular signal for promotion of biofilm formation, nasopharyngeal carriage and invasion of the lung. RESULTS: In this work, NeuNAc and its metabolic derivative N-acetyl mannosamine (ManNAc) were...

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PMID: 22963456
DOI: 10.1186/1471-2180-12-200

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